They marched down Elm Street and were met by a number of supportive passersby and drivers. After passing through Center City Park, they turned and headed back to where they started for a rally.
The demonstration comes as Republican lawmakers have proposed government budget cuts that, among other things, threaten funding of Planned Parenthood.
Some of the pro-choice advocates traveled from Chapel Hill to attend. The word was primarily spread via Facebook. There was a significant age-range among the attendees, and one held a sign reading "I vote in four years and I don't forget."
Above, protesters cross Market Street downtown. Photo by Eric Ginsburg. Jordan Green contributed to this report.